Exogenous endothelin-1 causes renal vasodilation in the fetal lamb.

Abstract

PURPOSE Endothelin-1 is known to be a potent vasoconstrictor. We investigated the effects and mechanisms of action of endothelin-1 and its receptors in regulating renal vascular tone in the fetal lamb. MATERIALS AND METHODS We observed the in vivo effects of endothelin-1, an endothelin-b receptor agonist (4-alanine-endothelin-1), endothelin-a receptor… (More)

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@article{Bogaert1996ExogenousEC, title={Exogenous endothelin-1 causes renal vasodilation in the fetal lamb.}, author={Guy A. Bogaert and Barry A. Kogan and Robert A. Mevorach and Jeffrey A. Wong and G R Gluckman and Jeffrey R. Fineman and Michael A. Heymann}, journal={The Journal of urology}, year={1996}, volume={156 2 Pt 2}, pages={847-53} }