Exogenous arachidonic acid inhibits A23187 stimulated macrophage leukotriene B4 synthesisin vitro

Abstract

It has become apparent over the last few years that cyclooxygenase and lipoxygenase metabolites of arachidonic acid (AA) interact to modulate macrophage functions. For example prostaglandin (PG) E2, a cyclooxygenase product, reversed the stimulation of macrophage lysosomal enzyme release induced by leukotriene (LT) C,, a lipoxygenase metabolite [1]. Further… (More)
DOI: 10.1007/BF01967197

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