It has become apparent over the last few years that cyclooxygenase and lipoxygenase metabolites of arachidonic acid (AA) interact to modulate macrophage functions. For example prostaglandin (PG) E2, a cyclooxygenase product, reversed the stimulation of macrophage lysosomal enzyme release induced by leukotriene (LT) C,, a lipoxygenase metabolite . Further… (More)
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