Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation.

@article{Deleyrolle2006ExogenousAF,
  title={Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation.},
  author={Lo{\"i}c Deleyrolle and Sophie Marchal-Victorion and C{\'e}cile Dromard and Vanessa Fritz and Monique Saunier and Jean-Charles Sabourin and Christophe Tran van Ba and Alain Privat and J P Hugnot},
  journal={Stem cells},
  year={2006},
  volume={24 3},
  pages={748-62}
}
Neurospheres (NSs) are clonal cellular aggregates composed of neural stem cells and progenitors. A comprehensive description of their proliferation and differentiation regulation is an essential prerequisite for their use in biotherapies. Cytokines are essential molecules regulating cell precursor fate. Using a gene-array strategy, we conducted a descriptive and functional analysis of endogenous cytokines and receptors expressed by spinal cord-derived NSs during their growth or their… CONTINUE READING

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