Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism.

Abstract

Mouse models of neuropsychiatric diseases provide a platform for mechanistic understanding and development of new therapies. We previously demonstrated that knockout of the mouse homolog of CNTNAP2 (contactin-associated protein-like 2), in which mutations cause cortical dysplasia and focal epilepsy (CDFE) syndrome, displays many features that parallel those… (More)
DOI: 10.1126/scitranslmed.3010257

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