Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation
@article{Li2011ExogenousSM, title={Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation}, author={Y. Li and Silvia Innocentin and D. Withers and N. Roberts and Alec R. Gallagher and Elena F Grigorieva and C. Wilhelm and M. Veldhoen}, journal={Cell}, year={2011}, volume={147}, pages={629-640} }
The body's surfaces form the interface with the external environment, protecting the host. These epithelial barriers are also colonized by a controlled diversity of microorganisms, disturbances of which can give rise to disease. Specialized intraepithelial lymphocytes (IELs), which reside at these sites, are important as a first line of defense as well as in epithelial barrier organization and wound repair. We show here that the aryl hydrocarbon receptor (AhR) is a crucial regulator in… CONTINUE READING
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Interventional Clinical Trial
This study evaluates the role of dietary L-tryptophan, an essential amino acid, in the
activation of a specific cellular component: the aryl hydrocarbon receptor.
Conditions | Diet Modification |
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Intervention | Dietary Supplement |
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