• DOI:10.1016/j.cell.2011.09.025
Corpus ID: 16090460

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

@article{Li2011ExogenousSM,
  title={Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation},
  author={Y. Li and Silvia Innocentin and D. Withers and N. Roberts and Alec R. Gallagher and Elena F Grigorieva and C. Wilhelm and M. Veldhoen},
  journal={Cell},
  year={2011},
  volume={147},
  pages={629-640}
}

Y. Li, Silvia Innocentin, +5 authors M. Veldhoen

Published 2011

Biology, Medicine

Cell

The body's surfaces form the interface with the external environment, protecting the host. These epithelial barriers are also colonized by a controlled diversity of microorganisms, disturbances of which can give rise to disease. Specialized intraepithelial lymphocytes (IELs), which reside at these sites, are important as a first line of defense as well as in epithelial barrier organization and wound repair. We show here that the aryl hydrocarbon receptor (AhR) is a crucial regulator in… CONTINUE READING

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