Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

  title={Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation},
  author={Y. Li and Silvia Innocentin and D. Withers and N. Roberts and Alec R. Gallagher and Elena F Grigorieva and C. Wilhelm and M. Veldhoen},
  • Y. Li, Silvia Innocentin, +5 authors M. Veldhoen
  • Published 2011
  • Biology, Medicine
  • Cell
  • The body's surfaces form the interface with the external environment, protecting the host. These epithelial barriers are also colonized by a controlled diversity of microorganisms, disturbances of which can give rise to disease. Specialized intraepithelial lymphocytes (IELs), which reside at these sites, are important as a first line of defense as well as in epithelial barrier organization and wound repair. We show here that the aryl hydrocarbon receptor (AhR) is a crucial regulator in… CONTINUE READING
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