Exogenous Reelin modifies the migratory behavior of neurons depending on cortical location.

@article{Britto2014ExogenousRM,
  title={Exogenous Reelin modifies the migratory behavior of neurons depending on cortical location.},
  author={Joanne M. Britto and Karen J Tait and Ean Phing Lee and Robin S Gamble and Mitsuharu Hattori and S S Tan},
  journal={Cerebral cortex},
  year={2014},
  volume={24 11},
  pages={2835-47}
}
Malformations of cortical development can arise when projection neurons generated in the germinal zones fail to migrate properly into the cortical plate. This process is critically dependent on the Reelin glycoprotein, which when absent leads to an inversion of cortical layers and blurring of borders. Reelin has other functions including supporting neuron migration and maintaining their trajectories; however, the precise role on glial fiber-dependent or -independent migration of neurons remains… CONTINUE READING
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