Exogenous Estradiol and Oxytocin Modulate Sex Differences in Hippocampal Reactivity and Episodic Memory

@article{Coenjaerts2021ExogenousEA,
  title={Exogenous Estradiol and Oxytocin Modulate Sex Differences in Hippocampal Reactivity and Episodic Memory},
  author={Marie Coenjaerts and Isabelle Trimborn and Berina Adrovic and Birgit Stoffel‐Wagner and Larry Cahill and Alexandra Philipsen and Ren{\'e} Hurlemann and Dirk Scheele},
  journal={bioRxiv},
  year={2021}
}
Considerable evidence supports sex differences in episodic memory, which may translate to heightened vulnerability to stress- and trauma-related disorders in women. The hormones estradiol and oxytocin both affect episodic memory, but possible underlying hormonal interactions have not been systemically tested in humans. To this end, healthy women (n = 111) and men (n = 115) received estradiol gel (2 mg) or placebo before the administration of intranasal oxytocin (24 IU) or placebo in a… 
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