Exocytosis in Astrocytes: Transmitter Release and Membrane Signal Regulation

@article{Guek2012ExocytosisIA,
  title={Exocytosis in Astrocytes: Transmitter Release and Membrane Signal Regulation},
  author={Alenka Gu{\vc}ek and Nina Vardjan and Robert Zorec},
  journal={Neurochemical Research},
  year={2012},
  volume={37},
  pages={2351-2363}
}
Astrocytes, a type of glial cells in the brain, are eukaryotic cells, and a hallmark of these are subcellular organelles, such as secretory vesicles. In neurons vesicles play a key role in signaling. Upon a stimulus—an increase in cytosolic concentration of free Ca2+ ([Ca2+]i)—the membrane of vesicle fuses with the presynaptic plasma membrane, allowing the exit of neurotransmitters into the extracellular space and their diffusion to the postsynaptic receptors. For decades it was thought that… CONTINUE READING
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