Existence of a lipid gradient in the upper stratum corneum and its possible biological significance

@article{Bonte1997ExistenceOA,
  title={Existence of a lipid gradient in the upper stratum corneum and its possible biological significance},
  author={Frederick J. Bonte and Alex Saunois and Patrick Pinguet and Alain Meybeck},
  journal={Archives of Dermatological Research},
  year={1997},
  volume={289},
  pages={78-82}
}
The internal stratum corneum lipid composition was investigated in relation to depth in vivo in healthy human volunteers by extraction following one, three or five strippings. Automated multiple development high-performance thin-layer chromatography (AMD-HPTLC) and gas chromatography (GC) followed by normalized principal component analysis showed a decrease in the amount of lipids extracted after one, three and five strippings. Between levels 0, 1, 3 and 5 the stratum corneum lipid composition… 

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