Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee

  title={Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee},
  author={Seiji Ohtori and Sumihisa Orita and Masaomi Yamashita and Tetsuhiro Ishikawa and Toshinori Ito and Tomonori Shigemura and Hideki Nishiyama and Shin Konno and Hideyuki Ohta and Masashi Takaso and Gen Inoue and Yawara Eguchi and Nobuyasu Ochiai and Shunji Kishida and Kazuki Kuniyoshi and Yasuchika Aoki and Gen Arai and Masayuki Miyagi and Hiroto Kamoda and Miyako Suzkuki and Junichi Nakamura and Takeo Furuya and Gou Kubota and Yoshihiro Sakuma and Yasuhiro Oikawa and Masahiko Suzuki and Takahisa Sasho and Koichi Nakagawa and Tomoaki Toyone and Kazuhisa Takahashi},
  booktitle={Yonsei medical journal},
PURPOSE Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction of subchondral bone junction, and induce neuropathic pain (NP). Our objective was to examine NP in the knees of OA patients using painDETECT (an NP questionnaire) and to evaluate the relationship between NP, pain intensity, and stage of OA. MATERIALS AND METHODS Ninety-two knee… CONTINUE READING
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