Exhaled nitric oxide in asthmatic children exposed to relevant allergens: effect of flunisolide.

@article{Piacentini2000ExhaledNO,
  title={Exhaled nitric oxide in asthmatic children exposed to relevant allergens: effect of flunisolide.},
  author={Giorgio Piacentini and Alessandro Bodini and Silvia Costella and Lucia Vicentini and Paola Mazzi and Yasuo Y. Suzuki and Diego G Peroni and Attilio Loris Boner},
  journal={The European respiratory journal},
  year={2000},
  volume={15 4},
  pages={
          730-4
        }
}
Inhaled corticosteroids are capable of reducing the level of exhaled nitric oxide (expiratory nitric oxide fraction (FE,NO)) in asthmatic patients in a dose-dependent fashion. The aim of this study was to evaluate whether or not treatment with an inhaled steroid can prevent changes in FE,NO after the exposure to relevant allergens, following avoidance, in asthmatic children allergic to house dust mite. Thirty-two house dust mite-allergy asthmatic children were randomly allocated to treatment… 
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Flunisolide Attenuates Nitric Oxide-Induced DNA Damage in Rat Trachea Epithelial Cells
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Exhaled nitric oxide has the potential to become a noninvasive method of assessing asthma control in the paediatric population, and is compared with other recognized markers.
Peripheral Inflammation in Patients with Asthmatic Symptoms but Normal Lung Function
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Patients with asthmatic symptoms but normal lung function have increased alveolar NO concentration and mildly elevated bronchial NO flux suggesting a more peripheral inflammation than in patients with asthma.
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