Exhaled breath profiling in diagnosing wheezy preschool children.

@article{Kant2013ExhaledBP,
  title={Exhaled breath profiling in diagnosing wheezy preschool children.},
  author={Kim D. G. van de Kant and Joep J B N van Berkel and Quirijn J{\"o}bsis and Val{\'e}ria Lima Passos and Ester M. M. Klaassen and Linda Jtm van der Sande and Onno Cp van Schayck and Johan C. de Jongste and Frederik Jan van Schooten and Eduard Derks and Edward Dompeling and Jan W. Dallinga},
  journal={The European respiratory journal},
  year={2013},
  volume={41 1},
  pages={
          183-8
        }
}
Although wheeze is common in preschool children, the underlying pathophysiology has not yet been disentangled. Volatile organic compounds (VOCs) in exhaled breath may serve as noninvasive markers of early wheeze. We aimed to assess the feasibility of VOC collection in preschool children, and to study whether a VOC profile can differentiate between children with and without recurrent wheeze. We included children (mean (range) age 3.3 (1.9-4.5) yrs) with (n=202) and without (n=50) recurrent… CONTINUE READING

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