Exfoliation syndrome: new genetic and pathophysiologic insights.

  title={Exfoliation syndrome: new genetic and pathophysiologic insights.},
  author={Julia Sein and Anat Galor and Anoop Sheth and Jonathan N. Kruh and Louis R. Pasquale and Carol Lynn Karp},
  journal={Current opinion in ophthalmology},
  volume={24 2},
PURPOSE OF REVIEW Exfoliation syndrome is the most common identifiable cause of glaucoma in the world. It has been associated with many ocular problems, such as secondary open angle glaucoma, corneal dysfunction, cataract, and zonular weakness, and may have systemic manifestations as well. This review focuses on recent genetic and pathophysiologic discoveries in the disease process. RECENT FINDINGS Exfoliation syndrome is a progressive age-related condition of the extracellular matrix (ECM… CONTINUE READING
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