Exertional oxygen uptake kinetics: a stamen of stamina?

  title={Exertional oxygen uptake kinetics: a stamen of stamina?},
  author={Brian Whipp and Harry B Rossiter and Susan A. Ward},
  journal={Biochemical Society transactions},
  volume={30 2},
The fundamental pulmonary O(2) uptake (.VO(2)) response to moderate, constant-load exercise can be characterized as (d.VO(2)/dt)(tau)+Delta.VO(2) (t)=Delta.VO(2SS) where Delta.VO(2SS) is the steady-state response, and tau is the time constant, with the .VO(2) kinetics reflecting intramuscular O(2) uptake (.QO(2)) kinetics, to within 10%. The role of phosphocreatine (PCr) turnover in .QO(2) control can be explored using (31)P-MR spectroscopy, simultaneously with .VO(2). Although tau.VO(2) and… CONTINUE READING
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