Exercise training prevents Ca2+ dysregulation in coronary smooth muscle from diabetic dyslipidemic yucatan swine.

@article{Witczak2006ExerciseTP,
  title={Exercise training prevents Ca2+ dysregulation in coronary smooth muscle from diabetic dyslipidemic yucatan swine.},
  author={Carol A Witczak and Brian R. Wamhoff and Michael S Sturek},
  journal={Journal of applied physiology},
  year={2006},
  volume={101 3},
  pages={752-62}
}
Aerobic exercise training is known to have profound cardioprotective effects in disease, yet cellular mechanisms remain largely undefined. We tested the hypothesis that increased sarcoplasmic reticulum Ca(2+) buffering and increased voltage-gated Ca(2+) channel density underlie coronary smooth muscle intracellular Ca(2+) (Ca(2+)(i)) dysregulation in… CONTINUE READING