Exercise training enhances baroreflex control of heart rate by a vagal mechanism in rabbits with heart failure.

  title={Exercise training enhances baroreflex control of heart rate by a vagal mechanism in rabbits with heart failure.},
  author={J L Liu and Jay Kulakofsky and Irving H. Zucker},
  journal={Journal of applied physiology},
  volume={92 6},
Moderate exercise training (Ex) enhances work capacity and quality of life in patients with chronic heart failure (CHF). We investigated the autonomic components of resting heart rate (HR) and the baroreflex control of HR in conscious, instrumented rabbits with pacing-induced CHF after Ex. Sham and CHF rabbits were exercise trained for 4 wk at 15-18 m/min, 6 days/wk. Arterial pressure and HR were recorded before and after metoprolol (1 mg/kg iv) or after atropine (0.2 mg/kg iv). Mean arterial… CONTINUE READING


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