Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat.

@article{Gilbert2012ExerciseTA,
  title={Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat.},
  author={Jeffrey S. Gilbert and Christopher T. Banek and Ashley J. Bauer and Anne Gingery and Karen M Needham},
  journal={Hypertension},
  year={2012},
  volume={60 6},
  pages={1545-51}
}
An imbalance between proangiogenic (vascular endothelial growth factor) and antiangiogenic (soluble fms-like tyrosine kinase 1) factors plays an important role in hypertension associated with reduced uteroplacental perfusion (RUPP). Exercise has been shown to stimulate proangiogenic factors, such as vascular endothelial growth factor, in both the pregnant and nonpregnant state; thus, we hypothesized that exercise training would attenuate both angiogenic imbalance and hypertension attributed to… CONTINUE READING
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adaptations to chronic placental ischemia in the rat

  • A Heltemes, A Gingery, +4 authors JS Gilbert
  • 2012

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