Exercise training and responsiveness of isolated coronary arteries.

  title={Exercise training and responsiveness of isolated coronary arteries.},
  author={P J Rogers and Todd L. Miller and Brent A. Bauer and Jose M G Brum and Alfred A. Bove and Paul Michel Vanhoutte},
  journal={Journal of applied physiology},
  volume={71 6},
Exercise is associated with release of catecholamines and vasoactive intestinal polypeptides. Recurrent exposure to catecholamines modifies the sensitivity of adrenoceptors. To test the hypothesis that exercise training may affect the sensitivity of the epicardial coronary arteries, we performed studies on isolated coronary arteries from male dogs capable of running on a treadmill. The animals were separated randomly into two groups: sedentary and exercise training. After 11 wk, rings of left… CONTINUE READING


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