Exercise training alters an anoxia-induced, glibenclamide-sensitive current in rat ventricular cardiocytes.

@article{Jew2002ExerciseTA,
  title={Exercise training alters an anoxia-induced, glibenclamide-sensitive current in rat ventricular cardiocytes.},
  author={Korinne N Jew and Russell Moore},
  journal={Journal of applied physiology},
  year={2002},
  volume={92 4},
  pages={1473-9}
}
The effect of training on properties of a sarcolemmal ATP-sensitive K+ current (I(K(ATP))) was examined in left ventricular cardiocytes isolated from sedentary (Sed) and trained (Tr) female Sprague-Dawley rats. Whole cell patch-clamp techniques were used to characterize I(K(ATP)), an anoxia-inducible, glibencamide-sensitive current. An anoxic condition was induced by superfusing cells with a buffer that was equilibrated with 100% N(2), maintained under a layer of argon, and that contained 2… CONTINUE READING