Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers

@inproceedings{Rijsingen2011ExerciseRV,
  title={Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers},
  author={Ingrid A W van Rijsingen and S. C. A. M. Bekkers and Simon M Schalla and Johanna F Hermans-van Ast and Gabriel Snoep and Becker S. N. Alzand and Yvonne H J M Arens and Arthur van den Wijngaard and Harry J. Crijns and Yigal M. Pinto},
  booktitle={Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation},
  year={2011}
}
AIMS: Hypertrophic cardiomyopathy (HCM) is a frequent cause of sudden cardiac death (SCD) due to exercise-related ventricular arrhythmias (ERVA); however the pathological substrate is uncertain. The aim was to determine the prevalence of ERVA and their relation with fibrosis as determined by cardiac magnetic resonance imaging (CMR) in carriers of an HCM causing mutation. METHODS: We studied the prevalence and origin of ERVA and related these with fibrosis on CMR in a population of 31 HCM… CONTINUE READING