Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome.

@article{Trseid2004ExerciseRP,
  title={Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome.},
  author={Marius Tr\oseid and Knut Tore Lappeg{\aa}rd and Tor Claudi and Jan Kristian Dam{\aa}s and Lars M\orkrid and Randi Brendberg and Tom Eirik Mollnes},
  journal={European heart journal},
  year={2004},
  volume={25 4},
  pages={349-55}
}
AIMS Inflammation plays an essential role in the atherosclerotic process, and chemokines such as monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) seem to play a pivotal role in the pathogenesis of atherosclerosis. A possible common inflammatory basis for the pathogenesis of type 2 diabetes, metabolic syndrome and atherosclerosis has been suggested. In this study we investigated the effect of physical exercise and the HMG-CoA reductase inhibitor pravastatin on peripheral… CONTINUE READING
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