Exercise-induced reversal of age-related declines of oxidative reactions, mitochondrial yield, and flavins in skeletal muscle of the rat.

@article{Beyer1984ExerciseinducedRO,
  title={Exercise-induced reversal of age-related declines of oxidative reactions, mitochondrial yield, and flavins in skeletal muscle of the rat.},
  author={Robert E. Beyer and Joseph W. Starnes and Dee W. Edington and Richard J. Lipton and Rebecca J. Compton and M A Kwasman},
  journal={Mechanisms of ageing and development},
  year={1984},
  volume={24 3},
  pages={309-23}
}
The ability of gastrocnemius muscle homogenates to catalyze the oxidation of succinate, glutamate + malate, pyruvate + malate, palmitoyl-coenzyme A, decanoylcarnitine and palmitoylcarnitine in the presence of ADP decreased by approximately 32% in sedentary male Sprague-Dawley rats between the ages of 9 and 25 months. Following 21 weeks of treadmill training (running), such homogenates from 25-month-old animals catalyzed oxidations 55% more rapidly than those from 25-month-old sedentary rats… CONTINUE READING