Exercise-induced endocannabinoid signaling is modulated by intensity

  title={Exercise-induced endocannabinoid signaling is modulated by intensity},
  author={David A. Raichlen and Adam D. Foster and Alexandre Seillier and Andrea Giuffrida and Gregory L. Gerdeman},
  journal={European Journal of Applied Physiology},
Endocannabinoids (eCB) are endogenous ligands for cannabinoid receptors that are densely expressed in brain networks responsible for reward. Recent work shows that exercise activates the eCB system in humans and other mammals, suggesting eCBs are partly responsible for the reported improvements in mood and affect following aerobic exercise in humans. However, exercise-induced psychological changes reported by runners are known to be dependent on exercise intensity, suggesting that any… CONTINUE READING
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Endocannabinoids at the synapse - retrograde signaling and presynaptic plasiticity in the brain. In: Kofalvi A (ed) Cannabinoids and the Brain

  • GL Gerdeman
  • 2008
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