Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury.

  title={Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury.},
  author={Scott K. Powers and John C Quindry and Andreas N. Kavazis},
  journal={Free radical biology & medicine},
  volume={44 2},
Myocardial ischemia-reperfusion (IR) injury is a major contributor to the morbidity and mortality associated with coronary artery disease. Muscular exercise is a countermeasure to protect against IR-induced cardiac injury in both young and old animals. Specifically, regular bouts of endurance exercise protect the heart against all levels of IR-induced injury. Proposed mechanisms to explain the cardioprotective effects of exercise include alterations in coronary circulation, expression of… CONTINUE READING
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