Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications.

Abstract

Regular physical exercise is recommended for the primary prevention of cardiovascular disease. Although the high prevalence of physical inactivity remains a formidable public health issue, participation in exercise programs and recreational sporting events, such as marathons and triathlons, is on the rise. Although regular exercise training reduces cardiovascular disease risk, recent studies have documented elevations in cardiac troponin (cTn) consistent with cardiac damage after bouts of exercise in apparently healthy individuals. At present, the prevalence, mechanism(s), and clinical significance of exercise-induced cTn release remains incompletely understood. This paper will review the biochemistry, prevalence, potential mechanisms, and management of patients with exercise-induced cTn elevations.

DOI: 10.1016/j.jacc.2010.03.037

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@article{Shave2010ExerciseinducedCT, title={Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications.}, author={Robert E Shave and Aaron L . Baggish and Keith P. George and Malissa J . Wood and Jurgen Scharhag and Gregory P. Whyte and David C. Gaze and Paul Daniel Thompson}, journal={Journal of the American College of Cardiology}, year={2010}, volume={56 3}, pages={169-76} }