Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation

@inproceedings{Biens2014ExerciseinducedAA,
  title={Exercise-induced AMPK and pyruvate dehydrogenase regulation is maintained during short-term low-grade inflammation},
  author={Rasmus Sj\orup Biens\o and Jesper H. Olesen and Line van Hauen and Simon Meinertz and Jens Frey Halling and Lasse Gliemann and Peter Plomgaard and Henriette Pilegaard},
  booktitle={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2014}
}
The aim of the present study was to examine the effect of lipopolysaccharide (LPS)-induced inflammation on AMP-activated protein kinase (AMPK) and pyruvate dehydrogenase (PDH) regulation in human skeletal muscle at rest and during exercise. Nine young healthy physically inactive male subjects completed two trials. In an LPS trial, the subjects received a single LPS injection (0.3 ng/kg body weight) and blood samples and vastus lateralis muscle biopsies were obtained before and 2 h after the LPS… CONTINUE READING
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