Exercise differentially regulates renalase expression in skeletal muscle and kidney.

  title={Exercise differentially regulates renalase expression in skeletal muscle and kidney.},
  author={B. Czarkowska-Pączek and M. Żendzian‐Piotrowska and K. Gala and M. Sobol and L. Pączek},
  journal={The Tohoku journal of experimental medicine},
  volume={231 4},
Renalase is a newly discovered amine oxidase and may lower blood pressure by metabolizing catecholamines. We have hypothesized that exercise and training may regulate renalase expression to control blood pressure. In this study, we investigated changes in renalase expression after exercise and training in white and red portion of the gastrocnemius muscle, kidney, and serum in rats. Rats were either untrained or subjected to six weeks of endurance training, which predominantly recruits red… Expand
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  • 20
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  • 20
  • PDF
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  • G. Moran
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2016
  • 21
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  • J. Xu, G. Li, +7 authors G. Desir
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  • The Journal of clinical investigation
  • 2005
  • 347
  • PDF
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  • G. Desir
  • Medicine
  • Current opinion in nephrology and hypertension
  • 2011
  • 66
Skeletal and heart muscle expression of PDGF-AA and VEGF-A after an acute bout of exercise and endurance training in rats.
  • 14
Regulation of blood pressure and cardiovascular function by renalase.
  • G. Desir
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  • Kidney international
  • 2009
  • 108
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  • 6
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  • 33
  • PDF
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  • 54
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  • 89
  • PDF
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  • 17
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