Exercise decreases plasma antioxidant capacity and increases urinary isoprostanes of IPF patients.

@article{Jackson2010ExerciseDP,
  title={Exercise decreases plasma antioxidant capacity and increases urinary isoprostanes of IPF patients.},
  author={Robert Max Jackson and Cristobal A Ramos and Chand Gupta and Orlando G{\'o}mez-Mar{\'i}n},
  journal={Respiratory medicine},
  year={2010},
  volume={104 12},
  pages={1919-28}
}
We tested whether markers of systemic oxidant stress were detectable in 29 typical IPF patients, and whether these increased after low level exercise. We obtained resting plasma for measurement of amino terminal pro brain natriuretic peptide (NT-proBNP), and plasma and urine samples for isoprostanes and total nitrite. Total antioxidant capacity (TAC) was measured in plasma, and H(2)O(2) was measured in urine. Subjects exercised at ˜50 W on a semi recumbent bicycle until limited by dyspnea… CONTINUE READING