Exercise capacity in young adults after hematopoietic cell transplantation in childhood

@article{berg2018ExerciseCI,
  title={Exercise capacity in young adults after hematopoietic cell transplantation in childhood},
  author={Anders {\"O}berg and Margareta Genberg and Andrei Malinovschi and Hans Hedenstr{\"o}m and Per Frisk},
  journal={American Journal of Transplantation},
  year={2018},
  volume={18},
  pages={417 - 423}
}
A symptom‐limited incremental cycle ergometer test was performed in 17 young adult patients treated with hematopoietic cell transplantation and total body irradiation for hematologic malignancies during childhood. These 17 young adult patients were compared with 17 sex‐ and age‐matched healthy control subjects. Assessments of pulmonary function, cardiac function, body composition, and levels of growth hormone were made. The median follow‐up was 17.7 years. Patients achieved 63.2% of the… 
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Does allogeneic stem cell transplantation in survivors of pediatric leukemia impact regular physical activity, pulmonary function, and exercise capacity?
TLDR
Although patients after allo-HSCT reported a good quality of life, regular physical activity and exercise capacity are reduced in survivors of stem cell transplantation, especially in adolescents who are treated with total body irradiation for conditioning.
Cardiorespiratory fitness and physical performance after childhood hematopoietic stem cell transplantation: a systematic review and meta-analysis
TLDR
An overview of childhood HSCT survivors’ status on these parameters compared with healthy controls is provided and current insights into clinical risk factors are discussed and muscle strength and physical performance seem to be impaired.
Effects of a physiotherapeutic protocol in cardiorespiratory, muscle strength, aerobic capacity and quality of life after hematopoietic stem cell transplantation.
Is health status impaired in childhood cancer survivors? A systematic review and meta-analysis.
Exploring pulmonary function and physical function in childhood cancer: a systematic review.
Cancer survivors exhibit a different relationship between muscle strength and health‐related quality of life/fatigue compared to healthy subjects
TLDR
It is shown that muscle strength was an important factor for improving QOL in cancer survivors and the findings of this study will be relevant in the context of planning rehabilitation for cancer survivors.

References

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