Exercise capacity in hypertrophic cardiomyopathy. Role of stroke volume limitation, heart rate, and diastolic filling characteristics.

@article{Lele1995ExerciseCI,
  title={Exercise capacity in hypertrophic cardiomyopathy. Role of stroke volume limitation, heart rate, and diastolic filling characteristics.},
  author={Sanjeev Lele and Helen L. Thomson and H Seo and Israel Belenkie and William J. McKenna and Michael P. Frenneaux},
  journal={Circulation},
  year={1995},
  volume={92 10},
  pages={2886-94}
}
BACKGROUND We previously showed that exercise capacity in patients with hypertrophic cardiomyopathy (HCM) is related to peak exercise cardiac output. Cardiac output augmentation during exercise is normally dependent on heart rate (HR) response and stroke volume (SV) augmentation by increased left ventricular end-diastolic volume and/or increased contractility. We hypothesized that in contrast to normal subjects, peak exercise capacity in patients with HCM is determined by the diastolic filling… CONTINUE READING
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