Exercise builds brain health: key roles of growth factor cascades and inflammation

  title={Exercise builds brain health: key roles of growth factor cascades and inflammation},
  author={Carl Cotman and Nicole C. Berchtold and Lori-Ann Christie},
  journal={Trends in Neurosciences},
Human and other animal studies demonstrate that exercise targets many aspects of brain function and has broad effects on overall brain health. The benefits of exercise have been best defined for learning and memory, protection from neurodegeneration and alleviation of depression, particularly in elderly populations. Exercise increases synaptic plasticity by directly affecting synaptic structure and potentiating synaptic strength, and by strengthening the underlying systems that support… CONTINUE READING
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