Exercise builds brain health: key roles of growth factor cascades and inflammation
@article{Cotman2007ExerciseBB, title={Exercise builds brain health: key roles of growth factor cascades and inflammation}, author={C. Cotman and N. Berchtold and Lori-Ann Christie}, journal={Trends in Neurosciences}, year={2007}, volume={30}, pages={464-472} }
Human and other animal studies demonstrate that exercise targets many aspects of brain function and has broad effects on overall brain health. The benefits of exercise have been best defined for learning and memory, protection from neurodegeneration and alleviation of depression, particularly in elderly populations. Exercise increases synaptic plasticity by directly affecting synaptic structure and potentiating synaptic strength, and by strengthening the underlying systems that support… CONTINUE READING
Paper Mentions
Interventional Clinical Trial
The proposed SYNERGIC trial is uniquely designed to evaluate the effect of aerobic and
progressive resistance training exercises, combined with cognitive training and Vitamin D3… Expand
Conditions | Mild Cognitive Impairment |
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Intervention | Dietary Supplement, Other |
Interventional Clinical Trial
The objective of this study is to investigate an aerobic exercise program as a treatment for
adults with persistent post-concussive symptoms (PPCS) following mild traumatic brain injury… Expand
Conditions | Brain Injuries, Traumatic, Concussion, Brain, Mild Traumatic Brain Injury, (+1 more) |
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Intervention | Behavioral |
Interventional Clinical Trial
Life expectancy and quality of human life are important indicator of the sustainable
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Conditions | Exercise Tolerance, Hypoxia, Altitude, Metabolic Disturbance, (+1 more) |
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Intervention | Device, Other |
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References
SHOWING 1-10 OF 111 REFERENCES
Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy
- Medicine, Biology
- The Journal of Neuroscience
- 2001
- 571
- PDF
Exercise: a behavioral intervention to enhance brain health and plasticity
- Psychology, Medicine
- Trends in Neurosciences
- 2002
- 2,270
- PDF
VEGF is necessary for exercise‐induced adult hippocampal neurogenesis
- Biology, Medicine
- The European journal of neuroscience
- 2003
- 704
Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
- Psychology, Medicine
- Neuroscience
- 2005
- 409
- PDF
Brain-derived neurotrophic factor and antidepressant activity.
- Medicine
- Current pharmaceutical design
- 2005
- 93
Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus
- Psychology, Medicine
- The Journal of Neuroscience
- 2001
- 889
- PDF
Effects of Exercise on Gene-Expression Profile in the Rat Hippocampus
- Biology, Medicine
- Neurobiology of Disease
- 2001
- 299
- PDF
The effects of growth hormone and IGF‐1 deficiency on cerebrovascular and brain ageing
- Medicine
- Journal of anatomy
- 2000
- 100