Exercise and the immune system: regulation, integration, and adaptation.

@article{Pedersen2000ExerciseAT,
  title={Exercise and the immune system: regulation, integration, and adaptation.},
  author={Bente Klarlund Pedersen and Laurie Hoffman-Goetz},
  journal={Physiological reviews},
  year={2000},
  volume={80 3},
  pages={
          1055-81
        }
}
Stress-induced immunological reactions to exercise have stimulated much research into stress immunology and neuroimmunology. It is suggested that exercise can be employed as a model of temporary immunosuppression that occurs after severe physical stress. The exercise-stress model can be easily manipulated experimentally and allows for the study of interactions between the nervous, the endocrine, and the immune systems. This review focuses on mechanisms underlying exercise-induced immune changes… 

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