Exercise and immobilization in aging animals: the involvement of oxidative stress and NF-kappaB activation.

@article{BarShai2008ExerciseAI,
  title={Exercise and immobilization in aging animals: the involvement of oxidative stress and NF-kappaB activation.},
  author={Marina Bar-Shai and Eli Carmeli and Predrag Ljubuncic and Abraham Zeev Reznick},
  journal={Free radical biology & medicine},
  year={2008},
  volume={44 2},
  pages={202-14}
}
In the early 1980s, the concept of threshold of age in exercise and aging was proposed. In several studies it was shown that subjecting young animals to short periods of moderate to intense exercise improved the biochemical and morphological status of their skeletal muscles. This was not the case for old animals subjected to the same exercise regimens. Thus, by measuring several muscle energy-providing enzymes as well as antioxidant enzymes it was demonstrated that their levels and activities… CONTINUE READING

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