Exercise and associated dietary extremes impact on gut microbial diversity

  title={Exercise and associated dietary extremes impact on gut microbial diversity},
  author={Siobhan F. Clarke and Eileen F. Murphy and {\'O}rla O’Sullivan and Alice Lucey and Maggie Humphreys and Aileen Hogan and Paula A Hayes and Maeve O'Reilly and Ian B. Jeffery and Ruth Wood-Martin and David M. Kerins and Eamonn M M Quigley and Reynolds Paul Ross and Paul W. O’Toole and Michael G. Molloy and {\'E}anna Cian Falvey and Fergus Shanahan and Paul D. Cotter},
  pages={1913 - 1920}
Objective The commensal microbiota, host immunity and metabolism participate in a signalling network, with diet influencing each component of this triad. In addition to diet, many elements of a modern lifestyle influence the gut microbiota but the degree to which exercise affects this population is unclear. Therefore, we explored exercise and diet for their impact on the gut microbiota. Design Since extremes of exercise often accompany extremes of diet, we addressed the issue by studying… 
TITLE: Exercise and the microbiota
The relationship between extreme levels of exercise, associated dietary habits and gut microbiota composition, and potential mechanisms by which exercise may exert a direct or indirect influence on gut microbiota are assessed.
Interplay Between Exercise and Gut Microbiome in the Context of Human Health and Performance
Taking into account the microbiota composition and its metabolic contribution to human host health could help in monitoring and modulating athletes' health and performance, and an integrated approach should help in the design of microbiome-based solutions for health or performance.
Gut microbiota: Tackling the effects of diet and exercise on the gut microbiota
  • K. Ray
  • Biology
    Nature Reviews Gastroenterology &Hepatology
  • 2014
More work is needed to prove that exercise has a direct effect on the gut microbiota and a causative role in changing the diversity of these microbes, as well as separate out the effects of exercise from the dietary changes that often accompany a healthy lifestyle in general.
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Diet and exercise play very important roles in the composition of the gut microbiota in the athletic and nonathletic individual, and there is evidence that suggests overall health benefits.
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The aim of the present review is to present an overview of the effects of physical exercise associated with diet on the characteristics of the intestinal microbiota.
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Microbiota could be an important tool to improve overall general health, performance, and energy availability while controlling inflammation and redox levels in endurance athletes.
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The GI tract is colonised by trillions of bacteria in a complex community collectively referred to as the gut microbiota, and the composition of the diet the authors consume is known to affect the microbial community composition.
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Current knowledge of the athletic gut microbiota and the factors that shape it are summarized to promote a more “health-associated” gut microbiota, including a higher abundance of health-promoting bacterial species, increased microbial diversity, functional metabolic capacity, and microbial-associated metabolites.
The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level
Differences in faecal microbiota between athletes and sedentary controls show even greater separation at the metagenomic and metabolomic than at compositional levels and provide added insight into the diet–exercise–gut microbiota paradigm.


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The authors' classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.
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Substantial insight is provided into the intricate mechanisms of bacterial regulation of the cross-talk between the host and gut microbiota and provides a rationale for the development of a treatment that uses this human mucus colonizer for the prevention or treatment of obesity and its associated metabolic disorders.