Exercise and Pharmacotherapy in the Treatment of Major Depressive Disorder

@article{Blumenthal2007ExerciseAP,
  title={Exercise and Pharmacotherapy in the Treatment of Major Depressive Disorder},
  author={J. Blumenthal and M. Babyak and P. Doraiswamy and L. Watkins and B. Hoffman and K. Barbour and S. Herman and W. E. Craighead and A. L. Brosse and R. Waugh and A. Hinderliter and A. Sherwood},
  journal={Psychosomatic Medicine},
  year={2007},
  volume={69},
  pages={587-596}
}
Objective: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressant medication (sertraline) and greater reductions in depression compared to placebo controls. Methods: Between October 2000 and November 2005, we performed a prospective, randomized controlled trial (SMILE study) with allocation concealment and blinded outcome assessment in a tertiary care teaching… Expand
732 Citations

Paper Mentions

Interventional Clinical Trial
To investigate the impact of a structured eight week exercise intervention as an add-on therapy in treating Major Depressive Disorder. Using behavioural techniques and neuroimaging… Expand
ConditionsMajor Depressive Disorder
InterventionBehavioral
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