Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell.

@article{Wang2009ExerciseAP,
  title={Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell.},
  author={Jong-Shyan Wang and Yee H. Chung and S T Chow},
  journal={Medicine and science in sports and exercise},
  year={2009},
  volume={41 1},
  pages={115-22}
}
PURPOSE Natural killer cells (NK) induce the death of tumor cells by perforin/granzyme-mediated cytotoxicity, whereas platelets reduce the capacity of NK to destroy tumor cells. Physical exercise affects both immune function and platelet activity because responses depend on type, intensity, and duration of exercise. This investigation explores how various exercise regimens influence platelet-impeded cytotoxicity of NK to nasopharyngeal carcinoma cells (NPC). METHODS Thirty sedentary men… CONTINUE READING