Exercise Intensity, Dose, and Cardiovascular Disease.


In ReplyDrs Lesser andMcCormacknote limitations to relying on LDL-C measurement as an intermediate end point to assess what physicians really want to improve, which is cardiovascular risk. Despite known limitations, LDL-C targets offered important advantages in our trial. First, when the trial was initiated, LDL-C targets were a dominant clinical guideline… (More)
DOI: 10.1001/jama.2016.0306


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