Exercise Improves Cognitive Responses to Psychological Stress through Enhancement of Epigenetic Mechanisms and Gene Expression in the Dentate Gyrus

@article{Collins2009ExerciseIC,
  title={Exercise Improves Cognitive Responses to Psychological Stress through Enhancement of Epigenetic Mechanisms and Gene Expression in the Dentate Gyrus},
  author={Andrew Collins and Louise E. Hill and Yalini Chandramohan and Daniel Whitcomb and Susanne K. Droste and Johannes M H M Reul},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={214 - 219}
}
BACKGROUND We have shown previously that exercise benefits stress resistance and stress coping capabilities. Furthermore, we reported recently that epigenetic changes related to gene transcription are involved in memory formation of stressful events. In view of the enhanced coping capabilities in exercised subjects we investigated epigenetic, gene expression and behavioral changes in 4-weeks voluntarily exercised rats. METHODOLOGY/PRINCIPAL FINDINGS Exercised and control rats coped… CONTINUE READING
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