Exercise, oxidative stress and ageing.

  title={Exercise, oxidative stress and ageing.},
  author={Anne McArdle and Malcolm J. Jackson},
  journal={Journal of anatomy},
  volume={197 Pt 4},
Skeletal muscle has the unique ability to increase the rate of oxygen usage during contraction. This has led several workers to suggest that by-products of this increased oxygen consumption, oxygen-derived free radicals, may be primarily responsible for exercise-induced damage to skeletal muscle. However, because of this rapidly changing redox state, skeletal muscle has developed a number of different endogenous mechanisms which adapt rapidly following a period of exercise. These include… CONTINUE READING

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