Exercise, alveolar macrophage function, and susceptibility to respiratory infection.

  title={Exercise, alveolar macrophage function, and susceptibility to respiratory infection.},
  author={J. Mark Davis and Marian L Kohut and Lisa H. Colbert and David Arthur Jackson and Abdul Ghaffar and Eugene P. Mayer},
  journal={Journal of applied physiology},
  volume={83 5},
The effects of exercise on susceptibility to respiratory infection were determined by using a murine model of intranasal challenge with herpes simplex type 1 virus (HSV-1). Two doses of treadmill exercise were assessed: moderate short-term (30 min) exercise and prolonged strenuous exercise to voluntary fatigue (2.5-3.5 h). Morbidity and mortality among exercised and control mice were compared after intranasal challenge with HSV-1. We also assessed the ability of alveolar macrophages to restrict… 

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