Exendin-4 protects mice from D-galactose-induced hepatic and pancreatic dysfunction

@inproceedings{Ahangarpour2018Exendin4PM,
  title={Exendin-4 protects mice from D-galactose-induced hepatic and pancreatic dysfunction},
  author={Akram Ahangarpour and Ali Akbar Oroojan and Mohammad Badavi},
  booktitle={Pathobiology of aging & age related diseases},
  year={2018}
}
Investigations into pharmaceutical intervention of pancreatic and hepatic dysfunction associated with metabolic disturbances have received relatively little attention. The aim of this study was to investigate the protective effects of exendin-4 in mice receiving D-galactose, a reducing sugar that triggers ROS production and inflammatory mediators affecting the pancreas and liver. Exendin-4 is an United States Food and Drug Administration (FDA) approved glucagon-like peptide that increases… CONTINUE READING