Exendin-4 Loaded Nanoparticles with a Lipid Shell and Aqueous Core Containing Micelles for Enhanced Intestinal Absorption.

Abstract

The purpose of this study was to formulate nanoparticles with an elaborate structure for oral delivery of exendin-4 using a simple preparation process. The nanoparticles possessed a mixed lipid shell and an aqueous core which contained drug-loaded micelles. Formulation was optimized by a central composite design and the structure of the nanoparticles was… (More)

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Cite this paper

@article{Chen2015Exendin4LN, title={Exendin-4 Loaded Nanoparticles with a Lipid Shell and Aqueous Core Containing Micelles for Enhanced Intestinal Absorption.}, author={Chunhui Chen and Xi Zhu and Yanfeng Dou and Juan Xu and Jian Zhang and Tingting Fan and Junrong Du and Ke Liu and Yihong Deng and Liyan Zhao and Yuan Huang}, journal={Journal of biomedical nanotechnology}, year={2015}, volume={11 5}, pages={865-76} }