Exendin-4 Decelerates Food Intake, Weight Gain, and Fat Deposition in Zucker Rats.

Abstract

Exendin-4 is a 39 amino acid peptide produced in the salivary gland of the Gila monster lizard. It has a 53% amino acid homology to the incretin hormone glucagon-like peptide-1 (GLP-1). Exendin-4 induces insulin release through activation of the GLP- 1 receptor but is a much more potent insulinotropic agent than GLP-1. Of critical importance for its… (More)
DOI: 10.1210/endo.141.6.7490

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Cite this paper

@article{Szayna2000Exendin4DF, title={Exendin-4 Decelerates Food Intake, Weight Gain, and Fat Deposition in Zucker Rats.}, author={Margarzata Szayna and Ma Ire E Doyle and Jennifer A Betkey and Harold W. Holloway and Richard G. S. Spencer and Nigel H. Greig and Josephine M. Egan}, journal={Endocrinology}, year={2000}, volume={141 6}, pages={1936-1941} }