Executive function and genetic predisposition to schizophrenia--the Maudsley family study.

@article{Birkett2008ExecutiveFA,
  title={Executive function and genetic predisposition to schizophrenia--the Maudsley family study.},
  author={Paul Brian Lawrie Birkett and Thordur Sigmundsson and Tonmoy Sharma and Timothea Toulopoulou and T. D. Griffiths and Adrianne Reveley and Robin MacGregor Murray},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2008},
  volume={147 3},
  pages={285-93}
}
Executive cognitive impairment has been found in families affected by schizophrenia and is a putative endophenotype. We wished to explore its genetic basis further by studying the association between impairment and genetic loading for schizophrenia. We studied 30 schizophrenia patients with a family history of schizophrenia, 53 of their nonpsychotic first-degree relatives (familial), 32 patients with schizophrenia but no known family history of psychosis, 52 of their first-degree relatives… CONTINUE READING
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