Execution mechanisms of programmed cell death by caspase (ICE/CED-3) family proteases.

Abstract

Molecular genetic study of Caenorhabditis elegans revealed the cell death-executing gene ced-3. Structural and functional similarities between CED-3 and mammalian ICE family (caspase) gene products provide the evidence that mammalian caspases are common mediators in executing programmed cell death. These findings suggest that the execution mechanisms of… (More)

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@article{Miura1997ExecutionMO, title={Execution mechanisms of programmed cell death by caspase (ICE/CED-3) family proteases.}, author={Mamoru Miura and Shin Hisahara and Tsutomu Araki and Hideyuki Okano}, journal={Heart and vessels}, year={1997}, volume={Suppl 12}, pages={66-70} }