Excretory-secretory products secreted by Paragonimus westermani delay the spontaneous cell death of human eosinophils through autocrine production of GM-CSF.

@article{Shin2003ExcretorysecretoryPS,
  title={Excretory-secretory products secreted by Paragonimus westermani delay the spontaneous cell death of human eosinophils through autocrine production of GM-CSF.},
  author={Myeong Heon Shin and Ju-Young Seoh and Hae-Young Lopilly Park and Hirohito Kita},
  journal={International archives of allergy and immunology},
  year={2003},
  volume={132 1},
  pages={
          48-57
        }
}
BACKGROUND Eosinophils play important roles in tissue inflammatory responses associated with helminth infections. Excretory-secretory products (ESP) produced by tissue-invasive helminths contain a large quantity of proteolytic enzymes that can modulate the host's immune responses. However, little is known regarding the roles of worm-derived products that are responsible for eosinophilic inflammatory responses in helminth infections. OBJECTIVE In the present study, we investigated whether ESP… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 46 REFERENCES