Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method.

@article{Xu2000ExcretionPI,
  title={Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method.},
  author={G. Xu and H. Schmid and X. Lu and H. Liebich and P. Lu},
  journal={Biomedical chromatography : BMC},
  year={2000},
  volume={14 7},
  pages={
          459-63
        }
}
  • G. Xu, H. Schmid, +2 authors P. Lu
  • Published 2000
  • Chemistry, Medicine
  • Biomedical chromatography : BMC
Modified nucleosides, formed post-transcriptionally in RNA by a number of modification enzymes, are excreted in abnormal levels in the urine of patients with malignant tumors. To test their usefulness as tumor markers, and to compare them with the conventional tumor markers, a reversed-phase high-performance liquid chromatographic (RP-HPLC) method and a factor analysis method have been used to study the excretion pattern of nucleosides of breast cancer patients. A clear cut differentiation of… Expand
47 Citations
Analysis of urinary nucleosides as helper tumor markers in hepatocellular carcinoma diagnosis.
  • 35
Analysis of urinary nucleosides as potential tumor markers in human colorectal cancer by high performance liquid chromatography/electrospray ionization tandem mass spectrometry.
  • W. Hsu, W. Chen, +6 authors C. Lai
  • Chemistry, Medicine
  • Clinica chimica acta; international journal of clinical chemistry
  • 2009
  • 65
A new way to fast and high resolution determination of modified nucleosides.
  • S. Studzińska, B. Buszewski
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  • 2012
  • 11
Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis
  • 41
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 16 REFERENCES
Patterns of urinary excretion of modified nucleosides.
  • 141
Modified Nucleosides and Cancer
  • G. Nass
  • Biology, Medicine
  • Recent Results in Cancer Research/Fortschritte der Krebsforschung/Progrès dans les recherches sur Ie cancer
  • 1983
  • 25
...
1
2
...