Excretion of epidermal growth factor (EGF) in diabetes.

  title={Excretion of epidermal growth factor (EGF) in diabetes.},
  author={A S Lev-Ran and David L Hwang and J. D. R. Miller and Zeev Josefsberg},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={192 3},
Excretion of epidermal growth factor (EGF) is decreased in renal failure. We assayed it in diabetes mellitus in an attempt to relate it to clinical parameters, esp. those of diabetic nephropathy. EGF excretion declined with age but in all age groups of diabetic patients was below the first percentile for controls. In 26 control and 34 prepubertal diabetic children excretion was correspondingly 1126 +/- 442 and 932 +/- 489 pmol/mmol creatinine (P = 0.087); in 26 control and 42 diabetic… CONTINUE READING