Excoecarianin, Isolated from Phyllanthus urinaria Linnea, Inhibits Herpes Simplex Virus Type 2 Infection through Inactivation of Viral Particles

@article{Cheng2011ExcoecarianinIF,
  title={Excoecarianin, Isolated from Phyllanthus urinaria Linnea, Inhibits Herpes Simplex Virus Type 2 Infection through Inactivation of Viral Particles},
  author={Hua-Yew Cheng and C. Yang and Ta-chen Lin and Liang-Tzung Lin and L. Chiang and Chun-ching Lin},
  journal={Evidence-based Complementary and Alternative Medicine : eCAM},
  year={2011},
  volume={2011}
}
Phyllanthus urinaria Linnea (Euphorbiaceae) is one of the traditional medicinal plants widely used by oriental people to treat various diseases. We have previously demonstrated that the acetone extract of P. urinaria inhibits herpes simplex virus type 2 (HSV-2) but not HSV-1 infection. In a continuing effort to clarify the antiviral mechanisms of P. urinaria, we isolated the pure compound excoecarianin from the whole plant of P. urinaria through acetone extraction, and investigated its anti-HSV… Expand
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